key term - Down's syndrome

Definition

Down's syndrome is a chromosomal disorder caused by the presence of an extra copy of chromosome 21. This leads to physical and intellectual developmental delays.

Related terms

Trisomy 21: Trisomy 21 is another term for Down's syndrome, referring to the presence of three copies (instead of the usual two) of chromosome 21.

Non-disjunction: Non-disjunction is a genetic error that occurs during meiosis when chromosomes fail to separate properly. It can lead to conditions like Down's syndrome.

Intellectual disability: Intellectual disability: Individuals with Down's syndrome often experience some level of intellectual disability, which refers to limitations in cognitive functioning and adaptive skills.