Spanish exploration of the Americas began with Columbus in 1492, leading to expeditions by Cortés, Coronado, and others. These journeys were driven by desires for wealth, religious conversion, and territorial expansion, shaping the future of the Southwest. In New Mexico, explorers like Coronado and Oñate encountered Pueblo communities, establishing settlements and missions. This period brought significant changes, including new crops and technologies, but also conflict, disease, and cultural suppression that continue to impact the region today.