Grignard reaction

Definition

A Grignard reaction involves the addition of an organomagnesium compound, known as a Grignard reagent, to a carbonyl group, leading to the formation of alcohols. It is a pivotal method in organic chemistry for creating carbon-carbon bonds.

Related terms

Organomagnesium compounds: These are chemical compounds that contain magnesium bonded to an organic group, acting as important intermediates in organic synthesis.

Carbonyl group: A functional group consisting of a carbon atom double-bonded to an oxygen atom, which is highly reactive and foundational in many organic reactions.

Nucleophilic acyl substitution: A fundamental reaction mechanism where a nucleophile replaces a leaving group in acyl compounds like carboxylic acids and their derivatives