Pyocyanin

Definition

Pyocyanin is a blue-green pigment produced by the bacterium Pseudomonas aeruginosa. It plays a role in the pathogenicity of infections, particularly those affecting skin and eyes.

5 Must Know Facts For Your Next Test

1. Pyocyanin can generate reactive oxygen species (ROS) causing cellular damage.
2. It interferes with host immune responses, helping Pseudomonas aeruginosa to establish infections.
3. Pyocyanin is often associated with chronic wounds and burn infections.
4. The pigment is soluble in water and can be detected by its blue-green color on infected tissues or growth media.
5. Its production is regulated by quorum sensing mechanisms in Pseudomonas aeruginosa.

Review Questions

Related terms

Pseudomonas aeruginosa:

A Gram-negative bacterium known for causing various infections, including those in the skin and eyes.

Reactive Oxygen Species (ROS): Chemically reactive molecules containing oxygen that can cause significant damage to cell structures.

Quorum Sensing:

A system of stimuli and response correlated to population density, used by bacteria for regulating gene expression.