Special populations in sports medicine require unique care for individuals with diverse physical, physiological, or medical conditions. This includes adaptive sports, paralympians, and considerations for disability classification, inclusion, and accessibility. Understanding these populations is crucial for providing effective care. Physiological considerations vary widely, from spinal cord injuries to visual impairments. Common injuries and conditions are often specific to each population. Assessment, treatment, and rehabilitation strategies must be tailored to individual needs, often involving multidisciplinary teams and specialized equipment.