Systems Biology
Sanger sequencing is a method used to determine the nucleotide sequence of DNA, developed by Frederick Sanger in the 1970s. This technique relies on selective incorporation of chain-terminating dideoxynucleotides during DNA replication, allowing researchers to generate fragments of varying lengths that can be analyzed for their sequences. It's foundational in genomics and has paved the way for advancements in next-generation sequencing technologies.
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