Technology and Engineering in Medicine
Sanger sequencing is a method for determining the nucleotide sequence of DNA, developed by Frederick Sanger in the 1970s. This technique uses chain-terminating dideoxynucleotides during DNA synthesis, which allows for the generation of fragments that can be separated by size and analyzed to reveal the sequence. It has been fundamental in the fields of genomics and proteomics, allowing researchers to analyze genetic information and understand the relationships between genes and proteins.
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