The Cramér-Rao Lower Bound (CRLB) is a theoretical lower limit on the variance of unbiased estimators, providing a benchmark for the efficiency of an estimator. It establishes that no unbiased estimator can have a variance smaller than the reciprocal of the Fisher Information, which reflects how much information a sample carries about an unknown parameter. This concept is crucial in evaluating the performance of different estimation techniques and understanding their efficiency in the context of statistical inference.
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