Serotonin

Definition

Serotonin is a neurotransmitter that plays a crucial role in mood regulation, sleep, and appetite. It is synthesized from the amino acid tryptophan and is primarily found in the gastrointestinal tract, blood platelets, and the central nervous system.

5 Must Know Facts For Your Next Test

1. Serotonin influences neurological wellness by regulating mood, anxiety, and happiness.
2. Dietary intake of tryptophan-rich foods can impact serotonin levels in the brain.
3. A deficiency in serotonin is associated with conditions like depression and anxiety disorders.
4. Gut health significantly impacts serotonin production as about 90% of serotonin is produced in the gastrointestinal tract.
5. Certain medications for depression, known as SSRIs (Selective Serotonin Reuptake Inhibitors), increase serotonin levels by blocking its reabsorption.

Review Questions

• How does dietary tryptophan influence serotonin levels?
• What percentage of serotonin is produced in the gastrointestinal tract?
• Name a class of medications that increase serotonin levels by blocking its reabsorption.

Related terms

Tryptophan:

An essential amino acid that serves as a precursor to serotonin.

Neurotransmitter: A chemical substance that transmits signals across synapses between neurons.

Selective Serotonin Reuptake Inhibitors (SSRIs):

A class of drugs used to treat depression by increasing levels of serotonin in the brain.