Interleukins

Definition

Interleukins are a group of cytokines that play crucial roles in the immune system by promoting the development and differentiation of T and B lymphocytes, as well as hematopoietic cells. They mediate communication between cells to regulate immune responses, inflammation, and hematopoiesis.

5 Must Know Facts For Your Next Test

1. Interleukins are produced primarily by leukocytes and act on other leukocytes.
2. They have various roles including promoting cell growth, differentiation, and motility.
3. Interleukins like IL-1 and IL-6 are key players in the inflammatory response.
4. IL-2 is critical for T-cell proliferation after antigen stimulation.
5. Dysregulation of interleukin production can lead to autoimmune diseases or chronic inflammation.

Review Questions

• What primary function do interleukins serve in the immune system?
• Which interleukin is essential for T-cell proliferation?
• How can dysregulation of interleukin production affect human health?

Related terms

Cytokines:

Proteins important in cell signaling that affect the behavior of cells.

T-Lymphocytes: A type of white blood cell that plays a central role in cell-mediated immunity.

Inflammation:

A biological response to harmful stimuli such as pathogens or damaged cells.