Sinusitis is the inflammation of the tissue lining the sinuses, often caused by infections, allergies, or other factors that block the sinuses. This condition can lead to symptoms such as nasal congestion, facial pain, and headaches, significantly impacting a person's quality of life. Antihistamines and decongestants are commonly used to alleviate these symptoms by reducing inflammation and opening up nasal passages, providing relief for those affected by sinusitis.