Prolactin-inhibiting hormone (PIH)

Definition

Prolactin-inhibiting hormone (PIH), also known as dopamine, is a neurohormone that inhibits the secretion of prolactin from the anterior pituitary gland. It plays a crucial role in regulating lactation and reproductive functions.

5 Must Know Facts For Your Next Test

1. PIH is primarily produced in the hypothalamus.
2. Its main function is to inhibit the release of prolactin from the anterior pituitary gland.
3. Prolactin levels are higher during pregnancy and breastfeeding, and PIH helps regulate these levels.
4. Dopamine acts as PIH when it travels through the hypophyseal portal system to reach the anterior pituitary.
5. A deficiency in PIH can lead to hyperprolactinemia, resulting in excessive milk production and potential reproductive issues.

Review Questions

• What is the primary source of prolactin-inhibiting hormone?
• How does PIH affect prolactin secretion?
• What condition can result from a deficiency in PIH?

Related terms

Prolactin: A hormone released by the anterior pituitary gland that stimulates milk production after childbirth.

Hypothalamus: A region of the brain responsible for producing hormones that control various bodily functions, including temperature regulation and hunger.

Anterior Pituitary Gland: The front portion of the pituitary gland that releases hormones regulating growth, reproduction, and lactation.