Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Prolactin-inhibiting hormone (PIH), also known as dopamine, is a neurohormone that inhibits the secretion of prolactin from the anterior pituitary gland. It plays a crucial role in regulating lactation and reproductive functions.
5 Must Know Facts For Your Next Test
PIH is primarily produced in the hypothalamus.
Its main function is to inhibit the release of prolactin from the anterior pituitary gland.
Prolactin levels are higher during pregnancy and breastfeeding, and PIH helps regulate these levels.
Dopamine acts as PIH when it travels through the hypophyseal portal system to reach the anterior pituitary.
A deficiency in PIH can lead to hyperprolactinemia, resulting in excessive milk production and potential reproductive issues.