Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Inhibin is a hormone produced by the gonads that inhibits the secretion of follicle-stimulating hormone (FSH) by the anterior pituitary gland. It plays a crucial role in the regulation of the reproductive system in both males and females.
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Inhibin is primarily produced by granulosa cells in females and Sertoli cells in males.
There are two types of inhibin: inhibin A and inhibin B, each with distinct roles in reproductive physiology.
In females, inhibin levels fluctuate during the menstrual cycle, peaking during the mid-luteal phase.
Inhibin B is more prominent in males and serves as an indicator of spermatogenesis.
High levels of inhibin can be used as a marker for certain ovarian tumors.
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Related terms
Follicle-Stimulating Hormone (FSH): A hormone secreted by the anterior pituitary gland that stimulates gamete production.
Granulosa Cells: Cells surrounding developing oocytes that produce estrogen and inhibin.
Sertoli Cells: Cells located within the seminiferous tubules of the testes that support sperm development and produce inhibin.