Growth hormone-releasing hormone (GHRH)

Definition

Growth hormone-releasing hormone (GHRH) is a peptide hormone produced in the hypothalamus that stimulates the release of growth hormone (GH) from the anterior pituitary gland. It plays a significant role in growth, metabolism, and overall endocrine regulation.

5 Must Know Facts For Your Next Test

1. GHRH is secreted by the arcuate nucleus of the hypothalamus.
2. The primary function of GHRH is to regulate the secretion of growth hormone from the anterior pituitary.
3. Growth hormone has multiple roles including stimulating growth, cell reproduction, and cell regeneration.
4. GHRH acts on specific receptors on somatotroph cells in the anterior pituitary to promote GH release.
5. GHRH secretion can be influenced by factors such as sleep, exercise, nutrition, and stress.

Review Questions

• What part of the brain produces GHRH?
• How does GHRH influence growth hormone levels?
• What factors can affect the secretion of GHRH?

Related terms

Hypothalamus: A region of the brain responsible for producing hormones that regulate various bodily functions.

Anterior Pituitary: The front portion of the pituitary gland that releases hormones such as growth hormone (GH), prolactin (PRL), and adrenocorticotropic hormone (ACTH).

Somatotrophs: Cells located in the anterior pituitary gland that produce and secrete growth hormone.