Growth hormone-inhibiting hormone (GHIH)

Definition

Growth hormone-inhibiting hormone (GHIH), also known as somatostatin, is a peptide hormone that inhibits the secretion of growth hormone (GH). It is produced by the hypothalamus and other tissues such as the pancreas and gastrointestinal tract.

5 Must Know Facts For Your Next Test

1. GHIH inhibits the release of growth hormone from the anterior pituitary gland.
2. The hypothalamus primarily produces GHIH, but it can also be found in the pancreas and gastrointestinal tract.
3. GHIH also regulates the secretion of several other hormones including insulin and glucagon.
4. Somatostatin analogs are used clinically to treat conditions like acromegaly and gigantism, which are caused by excessive growth hormone secretion.
5. GHIH plays a role in regulating digestive processes by inhibiting gastric acid secretion.

Review Questions

Related terms

Growth Hormone (GH): A peptide hormone that stimulates growth, cell reproduction, and regeneration in humans.

Hypothalamus:

A region of the brain responsible for producing hormones that control various bodily functions, including temperature regulation and hunger.

Anterior Pituitary Gland: The front portion of the pituitary gland that releases various hormones including GH, TSH, ACTH, FSH, LH, and prolactin.