The Descent from the Cross refers to the biblical scene depicting the removal of Jesus Christ's body from the crucifix after his crucifixion, a moment that has been a significant subject in Christian art. This scene captures themes of sorrow, redemption, and the human experience of loss, making it a popular subject for artists during the Mannerist and Baroque periods. Artists often portrayed it with dramatic emotional intensity and dynamic compositions, reflecting the evolving artistic styles and religious sentiments of the time.