Written by the Fiveable Content Team • Last updated September 2025
Verified for the 2026 exam
Verified for the 2026 exam•Written by the Fiveable Content Team • Last updated September 2025
Definition
Epistasis is when the alleles of one gene mask or alter the expression of another gene. It occurs when the phenotypic effect of one gene depends on the presence or absence of certain alleles at another gene.
Related terms
Gene interaction: Gene interaction refers to how different genes can interact with each other to produce a certain phenotype. It includes phenomena like epistasis, where one gene affects the expression of another.