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Palmitic Acid

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Organic Chemistry

Definition

Palmitic acid is a saturated fatty acid that is commonly found in various lipids, including waxes, fats, and oils. It plays important roles in the formation of soap, the structure of phospholipids, and the metabolic processes of fatty acid catabolism and biosynthesis.

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5 Must Know Facts For Your Next Test

  1. Palmitic acid is the most common saturated fatty acid found in many animal and plant fats and oils.
  2. It is a key component of the fatty acid chains in triacylglycerols, the primary storage form of lipids in the body.
  3. Palmitic acid is an important precursor in the biosynthesis of longer-chain fatty acids and other lipids.
  4. The carboxylic acid group of palmitic acid allows it to be incorporated into phospholipids, which are essential structural components of cell membranes.
  5. During the catabolism of triacylglycerols, palmitic acid undergoes β-oxidation to generate acetyl-CoA, which can then be used in the citric acid cycle to produce ATP.

Review Questions

  • Explain the role of palmitic acid in the formation of waxes, fats, and oils.
    • Palmitic acid is a common saturated fatty acid that is a key component of many naturally occurring lipids, including waxes, fats, and oils. It is found in the fatty acid chains of triacylglycerols, which are the primary storage form of lipids in the body and in many plant and animal sources. The presence of palmitic acid contributes to the physical properties and melting points of these lipid molecules, influencing their ability to function as energy stores, insulation, and structural components.
  • Describe the significance of palmitic acid in the formation of soap.
    • The carboxylic acid group of palmitic acid allows it to undergo saponification, the chemical reaction that produces soap. When palmitic acid reacts with a strong base, such as sodium hydroxide or potassium hydroxide, it forms a salt, which is the active ingredient in soap. The resulting soap molecules have a hydrophilic head (the carboxylate group) and a hydrophobic tail (the hydrocarbon chain), giving them the ability to emulsify and remove dirt, grease, and other lipophilic substances from the skin and surfaces.
  • Analyze the role of palmitic acid in the biosynthesis of fatty acids and the catabolism of triacylglycerols.
    • Palmitic acid is an important precursor in the biosynthesis of longer-chain fatty acids, as it can be elongated and desaturated to produce other lipids. Additionally, during the catabolism of triacylglycerols, palmitic acid undergoes β-oxidation, a process that breaks down the fatty acid chain to generate acetyl-CoA. This acetyl-CoA can then enter the citric acid cycle to produce ATP, the primary energy currency of the cell. The ability of palmitic acid to be both synthesized and catabolized highlights its central role in lipid metabolism and energy production within the body.

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