Transferrin

Definition

Transferrin is a glycoprotein primarily responsible for the transport of iron throughout the bloodstream to various tissues. It plays a crucial role in maintaining iron homeostasis and supporting various physiological functions, including neurological and hematologic wellness.

5 Must Know Facts For Your Next Test

1. Transferrin levels are often measured to evaluate iron deficiency anemia or iron overload conditions.
2. Low transferrin saturation can indicate iron deficiency, while high saturation can suggest hemochromatosis.
3. Iron carried by transferrin is vital for the synthesis of hemoglobin in red blood cells.
4. In neurological health, sufficient levels of transferrin-bound iron are essential for proper brain function and myelin formation.
5. Malnutrition or chronic diseases can alter transferrin levels, impacting both neurological and hematological systems.

Review Questions

• What role does transferrin play in the body's management of iron?
• How can transferrin saturation levels help diagnose different health conditions?
• Why is transferrin important for both neurological and hematological wellness?

Related terms

Ferritin:

A protein that stores iron and releases it when needed by the body.

Hemoglobin: An iron-containing protein in red blood cells responsible for transporting oxygen from the lungs to the rest of the body.

Iron Deficiency Anemia: A condition where a lack of adequate iron leads to insufficient production of hemoglobin, causing fatigue and weakness.