Opsonins

Definition

Opsonins are molecules that enhance phagocytosis by marking antigens for an immune response. They bind to the surface of pathogens, making them more recognizable to phagocytic cells.

5 Must Know Facts For Your Next Test

1. Opsonins include antibodies and components of the complement system like C3b.
2. They play a crucial role in innate immunity by promoting the clearance of pathogens.
3. Phagocytes have receptors that specifically recognize opsonins bound to pathogens.
4. Opsonization increases the efficiency of pathogen clearance compared to non-opsonized targets.
5. Deficiencies in opsonin production can lead to increased susceptibility to infections.

Review Questions

• What are two main types of opsonins involved in the immune response?
• How do opsonins enhance the process of phagocytosis?
• Why is opsonization important for innate immunity?

Related terms

Phagocytosis: The process by which phagocytic cells engulf and digest microorganisms and cellular debris.

Complement System: A group of proteins that work with antibodies to destroy pathogens.

Antibodies: Proteins produced by B cells that specifically bind to antigens and neutralize them or mark them for destruction.