🦠microbiology review

Herpes simplex virus

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Herpes simplex virus (HSV) is a double-stranded DNA virus that causes infections in humans, characterized by latent and recurrent infections. There are two main types: HSV-1 primarily causes oral herpes, while HSV-2 mainly causes genital herpes.

5 Must Know Facts For Your Next Test

  1. HSV has two main types: HSV-1 and HSV-2.
  2. The virus can establish latency in nerve cells, leading to recurrent infections.
  3. HSV-1 is commonly transmitted through oral contact, while HSV-2 is typically spread through sexual contact.
  4. Antiviral medications like acyclovir can reduce symptoms but do not cure the infection.
  5. HSV can be diagnosed through PCR testing, viral cultures, or serological tests.

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