The resolution rule is a fundamental rule of inference used in propositional and first-order logic, which allows for deriving a new clause from two existing clauses containing complementary literals. This technique is essential for automated theorem proving and logical reasoning, as it provides a systematic way to derive conclusions and check the validity of arguments. By applying the resolution rule, one can effectively refute a conjecture by showing that its negation leads to a contradiction, thus establishing its truth through refutation proofs.