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Recessive lethal

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

A recessive lethal allele is a type of genetic mutation that results in the death of an organism when present in a homozygous recessive state. Heterozygous individuals carrying one copy of the lethal allele typically survive and can pass the allele to their offspring.

5 Must Know Facts For Your Next Test

  1. Recessive lethal alleles often result in embryonic or early postnatal death.
  2. These alleles usually remain hidden in heterozygous carriers.
  3. Gregor Mendel's experiments laid foundational work, but he did not specifically identify lethal alleles.
  4. Recessive lethal alleles can be identified through breeding experiments and pedigree analysis.
  5. In some populations, these alleles can persist due to the survival advantage conferred by the heterozygous state.

Review Questions

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