Gcn5 is a histone acetyltransferase (HAT) that plays a crucial role in the regulation of gene expression in eukaryotic cells. It is part of the Gcn5/PCAF family and is known for modifying histones, particularly by adding acetyl groups to lysine residues, which leads to an open chromatin structure that facilitates transcription. This modification is essential for the recruitment of transcription factors and RNA polymerase II to promoters, thereby enhancing transcriptional activity.
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