Pacinian corpuscle

Definition

Pacinian corpuscles are specialized nerve endings located in the dermis and hypodermis layers of the skin, responsible for sensing deep pressure and vibration. They are oval-shaped structures encapsulated by concentric layers of connective tissue that act to amplify mechanical signals to the nerve.

Related terms

Dermis:

The second layer of skin that houses blood vessels, nerves, glands, and hair follicles, providing nutrients and support.

Hypodermis:

The deepest layer of skin composed mainly of fat and connective tissue which helps insulate the body and protect underlying muscles and organs.

Mechanoreceptor: A sensory receptor that responds to mechanical pressure or distortion, including touch, pressure, stretch, motion, and sound