Pharmacology for Nurses

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Sinemet

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Pharmacology for Nurses

Definition

Sinemet is a combination medication containing levodopa and carbidopa, used to treat symptoms of Parkinson's disease. Levodopa converts to dopamine in the brain, while carbidopa prevents levodopa breakdown before it reaches the brain.

5 Must Know Facts For Your Next Test

  1. Sinemet helps manage motor symptoms such as tremors, stiffness, and slowness.
  2. Carbidopa in Sinemet reduces peripheral side effects like nausea and cardiovascular issues.
  3. The typical administration of Sinemet is oral tablets taken multiple times a day.
  4. Sinemet can interact with other medications and certain foods high in protein.
  5. Long-term use may lead to motor complications such as dyskinesia (involuntary movements).

Review Questions

  • What are the two main components of Sinemet?
  • How does carbidopa enhance the effectiveness of levodopa in Sinemet?
  • What are some potential long-term side effects of using Sinemet?
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