Prostaglandin analogues

Definition

Prostaglandin analogues are medications that mimic the action of prostaglandins. They are primarily used to reduce intraocular pressure in patients with glaucoma or ocular hypertension.

5 Must Know Facts For Your Next Test

1. Prostaglandin analogues increase the outflow of aqueous humor through the uveoscleral pathway.
2. Common examples include latanoprost, bimatoprost, and travoprost.
3. These medications are typically administered once daily, usually in the evening.
4. Side effects may include eye redness, eyelash growth, and changes in iris pigmentation.
5. They are often preferred due to their efficacy and lower incidence of systemic side effects compared to other antiglaucoma drugs.

Review Questions

• What is the primary mechanism by which prostaglandin analogues reduce intraocular pressure?
• Name two common side effects associated with prostaglandin analogues.
• Why are prostaglandin analogues often administered in the evening?

Related terms

Beta-blockers: Medications that reduce intraocular pressure by decreasing aqueous humor production.

Alpha agonists: Drugs that lower intraocular pressure by reducing fluid production and increasing drainage.

Carbonic anhydrase inhibitors: Medications that decrease aqueous humor production to lower intraocular pressure.