Bloxiverz

Definition

Bloxiverz is a brand name for neostigmine methylsulfate, a cholinesterase inhibitor used to reverse neuromuscular blockade after surgery. It increases acetylcholine levels at neuromuscular junctions to improve muscle strength.

5 Must Know Facts For Your Next Test

1. Bloxiverz is primarily used in the management of myasthenia gravis and reversal of non-depolarizing neuromuscular blockade.
2. The drug works by inhibiting acetylcholinesterase, thereby increasing acetylcholine availability at synaptic clefts.
3. It is administered intravenously and dosage must be carefully monitored due to its potency.
4. Common side effects include bradycardia, increased salivation, and muscle cramps.
5. Contraindications include mechanical obstruction of the gastrointestinal or urinary tracts.

Review Questions

• What is the primary mechanism of action for Bloxiverz?
• List two common side effects associated with Bloxiverz.
• Why must Bloxiverz dosage be carefully monitored?

Related terms

Myasthenia Gravis: An autoimmune disorder that causes weakness in the skeletal muscles.

Acetylcholinesterase Inhibitors: A class of drugs that prevent the breakdown of acetylcholine, improving nerve signal transmission.

Neuromuscular Blockade: A medical procedure or condition where muscle relaxants are used to block transmission at the neuromuscular junction.