Neuroscience
pKa is a measure of the acidity of a substance, specifically the negative logarithm of the acid dissociation constant (Ka). It indicates how easily a proton (H+) can be removed from an acid, and is crucial in understanding the behavior of neurotransmitters and their receptors during synaptic transmission. The lower the pKa value, the stronger the acid, which impacts the ionization states of neurotransmitters and affects their interaction with receptors.
congrats on reading the definition of pKa. now let's actually learn it.