Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Whooping cough, also known as pertussis, is a highly contagious bacterial infection of the respiratory tract caused by Bordetella pertussis. It is characterized by severe coughing fits followed by a high-pitched 'whoop' sound during inhalation.
5 Must Know Facts For Your Next Test
Whooping cough is caused by the Gram-negative bacterium Bordetella pertussis.
The DTaP vaccine protects against whooping cough, diphtheria, and tetanus.
Bordetella pertussis produces several toxins that damage the respiratory tract and lead to the characteristic symptoms of whooping cough.
Infants are at the highest risk for severe complications from whooping cough, including pneumonia and death.
Laboratory diagnosis of whooping cough often involves polymerase chain reaction (PCR) testing or culture from nasopharyngeal swabs.
A Gram-negative bacterium that causes whooping cough.
DTaP Vaccine: A combination vaccine that protects against diphtheria, tetanus, and pertussis.
Respiratory Tract Infection: An infection occurring in any part of the respiratory system, including diseases such as bronchitis, pneumonia, and influenza.