Microbiology

study guides for every class

that actually explain what's on your next test

Polyclonal antibodies

from class:

Microbiology

Definition

Polyclonal antibodies are a mixture of antibodies produced by different B cell clones in the body, each recognizing a different epitope on the same antigen. They are commonly used in research and diagnostic laboratories to detect antigens due to their high sensitivity.

congrats on reading the definition of polyclonal antibodies. now let's actually learn it.

ok, let's learn stuff

5 Must Know Facts For Your Next Test

  1. Polyclonal antibodies can recognize multiple epitopes on a single antigen, which increases their binding strength.
  2. They are typically produced by immunizing an animal with an antigen and then collecting the serum.
  3. Polyclonal antibodies are less specific than monoclonal antibodies but offer higher sensitivity for detecting antigens.
  4. They can be used in various laboratory techniques including ELISA, Western Blotting, and Immunohistochemistry.
  5. The production of polyclonal antibodies is generally faster and less expensive compared to monoclonal antibodies.

Review Questions

  • What is the primary advantage of polyclonal antibodies over monoclonal antibodies?
  • How are polyclonal antibodies typically produced?
  • In what laboratory techniques are polyclonal antibodies commonly used?

"Polyclonal antibodies" also found in:

© 2024 Fiveable Inc. All rights reserved.
AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.
Glossary
Guides