🦠microbiology review

Last universal common ancestor (LUCA)

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The Last Universal Common Ancestor (LUCA) is the most recent common ancestor of all current life on Earth, estimated to have lived around 3.5 to 3.8 billion years ago. It represents a key node in the tree of life from which all prokaryotic and eukaryotic organisms diverged.

5 Must Know Facts For Your Next Test

  1. LUCA is not a single organism but a population of organisms sharing genetic characteristics.
  2. It possessed basic cellular structures like ribosomes and was likely capable of DNA replication, transcription, and translation.
  3. LUCA's environment was anaerobic, meaning it thrived in an oxygen-free environment.
  4. Genomic analyses suggest that LUCA had features common to both bacteria and archaea.
  5. Studying LUCA helps scientists understand the early evolution and diversification of life forms.

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