Enteropathogenic E. coli (EPEC)

Definition

Enteropathogenic E. coli (EPEC) is a type of Escherichia coli that causes diarrhea, primarily in infants and young children. It attaches to the intestinal lining and disrupts normal gut function.

5 Must Know Facts For Your Next Test

1. EPEC is a major cause of infantile diarrhea in developing countries.
2. EPEC does not produce Shiga toxin, which differentiates it from other E. coli strains like EHEC.
3. The bacteria adhere to intestinal epithelial cells using bundle-forming pili (BFP).
4. EPEC creates characteristic attaching and effacing lesions on the intestinal mucosa.
5. Diagnosis typically involves stool culture and detection of specific virulence genes via PCR.

Review Questions

• What primary age group is most affected by Enteropathogenic E. coli?
• How does EPEC differ from Enterohemorrhagic E. coli (EHEC) in terms of toxin production?
• What are the distinctive lesions called that are formed by EPEC on the intestinal lining?

Related terms

Enterotoxigenic E. coli (ETEC): A type of E. coli that produces enterotoxins causing traveler's diarrhea.

Enterohemorrhagic E. coli (EHEC): A strain of E. coli known for producing Shiga toxin leading to severe bloody diarrhea.

Bundle-forming pili (BFP): Hair-like appendages used by some bacteria, including EPEC, for attachment to host cells.