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Diphtheria

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Microbiology

Definition

Diphtheria is a serious bacterial infection caused by Corynebacterium diphtheriae, affecting the mucous membranes of the respiratory tract. It produces a toxin leading to severe respiratory issues and can be fatal if untreated.

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5 Must Know Facts For Your Next Test

  1. Diphtheria is primarily transmitted through respiratory droplets from coughing or sneezing.
  2. The hallmark symptom includes a thick, gray coating on the throat and tonsils.
  3. Corynebacterium diphtheriae is a Gram-positive bacterium.
  4. The diphtheria toxin inhibits protein synthesis in host cells, leading to cell death.
  5. Vaccination with the DTaP vaccine provides immunity against diphtheria.

Review Questions

  • What bacterium causes diphtheria and how does it affect the body?
  • Describe the primary mode of transmission for diphtheria.
  • What is the role of vaccination in preventing diphtheria?

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