Mathematical and Computational Methods in Molecular Biology
BAM, or Binary Alignment/Map format, is a binary version of the Sequence Alignment/Map (SAM) format that is used to store large sequence data efficiently. It facilitates the storage of aligned sequences, allowing for faster access and manipulation compared to its text-based counterpart. BAM files are crucial for bioinformatics applications, particularly in the analysis of high-throughput sequencing data, as they optimize both space and speed for handling extensive datasets.
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