Intro to Computational Biology
Alternative splicing is a process by which a single gene can lead to the production of multiple different protein isoforms by varying the combination of exons included in the final mRNA transcript. This mechanism allows for a diverse range of proteins to be generated from a limited number of genes, significantly enhancing the complexity and functionality of the proteome. In gene prediction, understanding alternative splicing is crucial as it affects how genes are annotated and the predicted protein products derived from them.
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