Immunobiology
Bcl-6 is a transcriptional repressor protein that plays a crucial role in the differentiation and function of immune cells, particularly in regulating the formation and maintenance of memory B cells and T follicular helper (Tfh) cells. By controlling gene expression, Bcl-6 helps to fine-tune the immune response and maintain a balance between activation and inhibition of immune cells, which is essential for effective long-term immunity.
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