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Prostate-specific antigen (PSA)

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Human Sexuality

Definition

Prostate-specific antigen (PSA) is a protein produced by cells of the prostate gland, primarily involved in the liquefaction of semen. Elevated levels of PSA in the blood can indicate various prostate conditions, including benign prostatic hyperplasia, prostatitis, and prostate cancer, making it a crucial marker in assessing male reproductive health.

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5 Must Know Facts For Your Next Test

  1. PSA levels can vary based on age, with higher levels often seen in older men due to natural changes in the prostate.
  2. A PSA test is commonly used as a screening tool for prostate cancer, although elevated levels do not guarantee cancer presence.
  3. Factors such as infections, recent ejaculation, or medical procedures involving the prostate can temporarily elevate PSA levels.
  4. The normal range for PSA levels is typically considered to be between 0 and 4 ng/mL, but this can vary based on individual circumstances.
  5. Monitoring PSA levels over time can help track changes and assist healthcare providers in making informed decisions regarding further testing or treatment.

Review Questions

  • How does the function of PSA relate to male reproductive health and its role in semen?
    • PSA plays a key role in male reproductive health by contributing to the fluid component of semen. It helps liquefy the seminal fluid after ejaculation, allowing sperm to swim freely and increase the chances of fertilization. Understanding PSA's function provides insight into how prostate health impacts overall reproductive capabilities.
  • Discuss the implications of elevated PSA levels and how they influence decisions about further diagnostic testing.
    • Elevated PSA levels can indicate various prostate conditions, leading to further diagnostic testing such as biopsies or imaging studies. While high PSA levels may suggest prostate cancer, they can also result from benign conditions like BPH or prostatitis. Thus, healthcare providers must consider these factors when deciding on the appropriate follow-up actions.
  • Evaluate the effectiveness of PSA testing in screening for prostate cancer and its associated controversies.
    • The effectiveness of PSA testing for prostate cancer screening is debated due to concerns over overdiagnosis and overtreatment. While it can detect cancers early, many detected cases may not pose a significant risk to life, leading to unnecessary treatments with potential side effects. Balancing the benefits of early detection against the risks of overtreatment remains a critical discussion in men's health care.

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