Ecotoxicology
Nucleotide excision repair is a critical DNA repair mechanism that removes damaged DNA segments, specifically those caused by environmental factors like UV radiation and chemical exposure. This process is vital for maintaining genomic integrity, as it prevents mutations that could lead to diseases, including cancer. By recognizing and excising bulky DNA adducts, nucleotide excision repair plays a significant role in protecting cells from genotoxicity and reducing the risk of mutagenicity and carcinogenicity.
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