❤️‍🩹First Aid Unit 11 – Allergic Reactions and Anaphylaxis

Allergies and anaphylaxis are serious health concerns that can range from mild discomfort to life-threatening emergencies. Understanding the triggers, symptoms, and proper responses is crucial for managing these conditions effectively and potentially saving lives. This guide covers essential information on identifying allergens, recognizing signs of allergic reactions, and providing appropriate first aid. It also details the use of epinephrine auto-injectors and strategies for long-term allergy management and prevention.

What Are Allergies and Anaphylaxis?

  • Allergies occur when the immune system overreacts to a normally harmless substance (allergen)
  • Allergic reactions can range from mild symptoms (itching, rash) to severe, life-threatening reactions (anaphylaxis)
  • Anaphylaxis is a serious, potentially fatal allergic reaction that affects multiple body systems
    • Can cause difficulty breathing, throat swelling, and a sudden drop in blood pressure
  • Allergies develop when the body produces antibodies called Immunoglobulin E (IgE) in response to an allergen
  • Subsequent exposure to the allergen triggers the release of chemicals like histamine, causing allergic symptoms
  • Allergies can be triggered by various substances, including foods, medications, insect stings, and latex
  • Anaphylaxis requires immediate medical attention and can progress rapidly, leading to shock and unconsciousness

Common Allergens and Triggers

  • Food allergens are among the most common triggers, with peanuts, tree nuts, shellfish, and milk being major culprits
  • Insect stings from bees, wasps, and hornets can cause severe allergic reactions in some individuals
  • Medications such as penicillin, aspirin, and certain anesthetics may trigger allergies
    • Reactions can occur even if the person has safely used the medication before
  • Latex found in gloves, balloons, and other products can cause allergic reactions, especially in healthcare workers
  • Environmental allergens like pollen, dust mites, and animal dander can trigger allergic rhinitis (hay fever) and asthma symptoms
  • Exercise-induced anaphylaxis may occur during or after physical activity, sometimes in combination with food allergens
  • Idiopathic anaphylaxis has no identifiable cause, making it challenging to diagnose and manage

Signs and Symptoms to Watch For

  • Mild allergic reactions may cause itching, rash, hives, or mild swelling (lips, face, eyes)
  • More severe reactions can lead to throat tightness, difficulty swallowing, and hoarseness
  • Respiratory symptoms include shortness of breath, wheezing, coughing, and nasal congestion
  • Anaphylaxis may cause abdominal pain, nausea, vomiting, and diarrhea
    • These symptoms can be mistaken for other conditions, delaying proper treatment
  • Cardiovascular signs of anaphylaxis include dizziness, fainting, rapid heartbeat, and low blood pressure
  • A sense of impending doom or anxiety can accompany severe allergic reactions
  • Symptoms can develop within seconds to minutes of exposure and may progress rapidly

Assessing the Severity of an Allergic Reaction

  • Quickly determine if the reaction is mild or potentially life-threatening
  • Ask the person about their allergy history and any previous severe reactions
  • Look for signs of respiratory distress, such as wheezing, gasping, or difficulty speaking
  • Check for signs of shock, including pale or clammy skin, weak pulse, and confusion
  • Monitor the person's level of consciousness and responsiveness
    • Deteriorating mental status is a red flag for anaphylaxis
  • If multiple body systems are affected or symptoms are rapidly worsening, treat as anaphylaxis
  • When in doubt, err on the side of caution and activate emergency medical services

First Aid Steps for Mild Allergic Reactions

  • Remove the person from the allergen source if possible (e.g., move away from a bee or wasp)
  • Administer an oral antihistamine, such as diphenhydramine (Benadryl), if available and not contraindicated
  • Apply a cold compress to the affected area to reduce swelling and itching
  • Monitor the person closely for any signs of symptom progression or difficulty breathing
  • If symptoms worsen or do not improve with initial treatment, seek medical attention
  • Advise the person to follow up with their healthcare provider for further evaluation and management
  • Educate the person on avoiding future exposure to the allergen and always carrying emergency medication

Emergency Response for Anaphylaxis

  • Call emergency medical services immediately and inform them that the person is experiencing anaphylaxis
  • If the person carries an epinephrine auto-injector (EpiPen), assist them in using it or administer it for them
    • Inject the EpiPen into the outer thigh, holding it in place for at least 3 seconds
  • Help the person lie down with their legs elevated to maintain blood flow to vital organs
  • Loosen tight clothing and remove any constricting items (e.g., jewelry) to facilitate breathing
  • If the person is unconscious and not breathing, begin CPR with rescue breaths
  • If symptoms do not improve or worsen after 5-15 minutes, administer a second dose of epinephrine if available
  • Stay with the person and monitor their condition until medical help arrives

Using an EpiPen and Other Treatments

  • Epinephrine is the first-line treatment for anaphylaxis and should be administered as soon as possible
  • EpiPens are designed for easy use by laypeople and come with instructions on the label
    • Remove the safety cap and firmly press the orange tip against the outer thigh until it clicks
  • Hold the EpiPen in place for at least 3 seconds to ensure full dose delivery
  • Massage the injection site for 10 seconds to enhance absorption and circulation
  • Antihistamines and bronchodilators (inhalers) can be used as adjunctive treatments but should not replace epinephrine
  • Corticosteroids may be administered by medical professionals to prevent delayed or biphasic reactions
  • People with a history of anaphylaxis should always carry two epinephrine auto-injectors and wear medical alert jewelry

Prevention and Long-term Management

  • Identifying and avoiding allergen triggers is crucial for preventing allergic reactions
  • People with food allergies should carefully read labels and inform restaurants of their allergies when dining out
  • Those with insect sting allergies should take precautions when outdoors, such as wearing protective clothing and carrying epinephrine
  • Immunotherapy (allergy shots) can help desensitize the immune system to specific allergens over time
    • This treatment is typically administered under the guidance of an allergist
  • Regularly visit an allergist to develop and update an allergy action plan
  • Always carry emergency medications, including epinephrine auto-injectors and antihistamines
  • Educate family, friends, and coworkers about your allergies and how to respond in an emergency
  • Consider wearing medical alert jewelry to inform others of your allergies in case you are unable to communicate


© 2024 Fiveable Inc. All rights reserved.
AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.

© 2024 Fiveable Inc. All rights reserved.
AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.