---
title: "AP Biology Data Analysis FRQ Practice"
description: "127 Analyze Data questions written in the AP format, each scored part by part."
canonical: "https://fiveable.me/ap-bio/frqs/data-analysis"
type: "frq-type-practice"
subject: "AP Biology"
---

# AP Biology Data Analysis FRQ Practice

## What the Data Analysis FRQ asks

This is FRQ 6 on the AP Biology exam. You get data in a graph or table, describe it, use it to evaluate a hypothesis, and explain the biology behind the results.

- **10 min**: suggested writing time
- **4 points**: 1 point for each part
- **50%**: of your score, for all six FRQs

| Part | What it asks | Points |
| --- | --- | --- |
| A: Read the data | Identify a value or pattern in the data | 1 |
| B: Describe the data | Describe a trend or comparison | 1 |
| C: Evaluate | Use the data to support or evaluate a hypothesis | 1 |
| D: Biology principle | Explain the biology behind the results | 1 |

## How Data Analysis FRQ practice works

1. **Read the full question.** The data and all four parts, A through D, laid out the way the exam shows them.
2. **Write on a 10-minute timer.** The time to plan for on exam day. Pause it or turn it off, and your response saves as you go.
3. **Submit for a score out of 4.** Your response is scored against the scoring guidelines written for that question. Your first score is included.

## All 127 questions

### Unit 1: Chemistry of Life (12)
- [Enzyme thermal stability and protein folding mutations](/ap-bio/frq-practice?id=69751e2039cb567763bc69ca&type=frq-6-analyze-data-short)
- [Enzyme structure and function in acidic environments](/ap-bio/frq-practice?id=6983c9b6ebf1103b6c528018&type=frq-6-analyze-data-short)
- [Enzyme mutations affecting toxin breakdown rates](/ap-bio/frq-practice?id=6983ca54ebf1103b6c52801f&type=frq-6-analyze-data-short)
- [Enzyme thermal stability and amino acid mutation effects](/ap-bio/frq-practice?id=6983cb96ebf1103b6c52802a&type=frq-6-analyze-data-short)
- [Arginine residue importance in alkaline enzyme stability](/ap-bio/frq-practice?id=6983cc46ebf1103b6c528030&type=frq-6-analyze-data-short)
- [Aquaporin channel structure and amino acid function](/ap-bio/frq-practice?id=6983ccd4ebf1103b6c528035&type=frq-6-analyze-data-short)
- [Enzyme tertiary structure and catalytic activity](/ap-bio/frq-practice?id=6983cf10ebf1103b6c528049&type=frq-6-analyze-data-short)
- [Amino acid mutations affecting aquaporin water transport function](/ap-bio/frq-practice?id=6983d015ebf1103b6c528056&type=frq-6-analyze-data-short)
- [Desaturase enzyme function in temperature acclimation](/ap-bio/frq-practice?id=6983d0fbebf1103b6c52805d&type=frq-6-analyze-data-short)
- [Enzyme structure, function, and amino acid substitutions](/ap-bio/frq-practice?id=6983d424ebf1103b6c528080&type=frq-6-analyze-data-short)
- [Enzyme thermal stability and amino acid interactions](/ap-bio/frq-practice?id=6983d4b7ebf1103b6c528087&type=frq-6-analyze-data-short)
- [Aquaporin mutations and water transport function](/ap-bio/frq-practice?id=6983d6abebf1103b6c52809a&type=frq-6-analyze-data-short)

### Unit 2: Cells (17)
- [CFTR protein localization and chloride transport dysfunction](/ap-bio/frq-practice?id=69751e5839cb567763bc69cc&type=frq-6-analyze-data-short)
- [Aquaporin protein structure and water transport function](/ap-bio/frq-practice?id=6983ca87ebf1103b6c528021&type=frq-6-analyze-data-short)
- [Water transport mechanisms in aquaporin mutant yeast](/ap-bio/frq-practice?id=6983cb0febf1103b6c528024&type=frq-6-analyze-data-short)
- [Aquaporin protein structure, localization, and water transport function](/ap-bio/frq-practice?id=6983cc4eebf1103b6c528031&type=frq-6-analyze-data-short)
- [TRP1 protein localization and calcium transport rates](/ap-bio/frq-practice?id=6983cce7ebf1103b6c528037&type=frq-6-analyze-data-short)
- [Aquaporin mutations and water transport efficiency](/ap-bio/frq-practice?id=6983ce00ebf1103b6c528040&type=frq-6-analyze-data-short)
- [Membrane fluidity, fatty acid composition, temperature adaptation](/ap-bio/frq-practice?id=6983ce13ebf1103b6c528042&type=frq-6-analyze-data-short)
- [Phosphate transporter protein function and regulation](/ap-bio/frq-practice?id=6983cea8ebf1103b6c528046&type=frq-6-analyze-data-short)
- [Aquaporin mutation effects on water transport function](/ap-bio/frq-practice?id=6983cfccebf1103b6c528052&type=frq-6-analyze-data-short)
- [Aquaporin function and water transport regulation](/ap-bio/frq-practice?id=6983d067ebf1103b6c528059&type=frq-6-analyze-data-short)
- [Aquaporin phosphorylation and water transport regulation](/ap-bio/frq-practice?id=6983d108ebf1103b6c528060&type=frq-6-analyze-data-short)
- [Membrane fluidity, fatty acid saturation, temperature adaptation](/ap-bio/frq-practice?id=6983d226ebf1103b6c52806b&type=frq-6-analyze-data-short)
- [Water transport mechanisms in plant root cells](/ap-bio/frq-practice?id=6983d22debf1103b6c52806d&type=frq-6-analyze-data-short)
- [Aquaporin mutations and cellular water transport efficiency](/ap-bio/frq-practice?id=6983d2c9ebf1103b6c528072&type=frq-6-analyze-data-short)
- [CAX1 protein function and cellular calcium transport](/ap-bio/frq-practice?id=6983d369ebf1103b6c528078&type=frq-6-analyze-data-short)
- [Glucose transporter protein structure and membrane localization](/ap-bio/frq-practice?id=6983d3fbebf1103b6c52807d&type=frq-6-analyze-data-short)
- [Glucose transport protein structure and function relationship](/ap-bio/frq-practice?id=6983d538ebf1103b6c52808c&type=frq-6-analyze-data-short)

### Unit 3: Cellular Energetics (16)
- [Compound X effects on mitochondrial ATP production](/ap-bio/frq-practice?id=69751e5439cb567763bc69cb&type=frq-6-analyze-data-short)
- [Brown adipose tissue thermogenesis and mitochondrial uncoupling protein function](/ap-bio/frq-practice?id=6983d007ebf1103b6c528053&type=frq-6-analyze-data-short)
- [Heat shock proteins protecting photosynthetic enzyme function](/ap-bio/frq-practice?id=6983d0bbebf1103b6c52805b&type=frq-6-analyze-data-short)
- [Proton gradient and ATP synthesis regulation](/ap-bio/frq-practice?id=6983d16eebf1103b6c528063&type=frq-6-analyze-data-short)
- [Cutinase enzyme mutations and catalytic activity](/ap-bio/frq-practice?id=6983d193ebf1103b6c528064&type=frq-6-analyze-data-short)
- [Thermal stability of photosynthetic electron transport and ATP synthesis](/ap-bio/frq-practice?id=6983d354ebf1103b6c528076&type=frq-6-analyze-data-short)
- [Enzyme mutations affecting protein stability and catalytic activity](/ap-bio/frq-practice?id=6983d392ebf1103b6c528079&type=frq-6-analyze-data-short)
- [Rubisco activase enzyme function in photosynthesis](/ap-bio/frq-practice?id=6983d3e0ebf1103b6c52807c&type=frq-6-analyze-data-short)
- [Mitochondrial respiration, electron transport, metabolic compensation](/ap-bio/frq-practice?id=6983d469ebf1103b6c528081&type=frq-6-analyze-data-short)
- [Photoinhibition tolerance mechanisms in mutant plants](/ap-bio/frq-practice?id=6983d4f1ebf1103b6c528089&type=frq-6-analyze-data-short)
- [Glycolytic enzyme mutations affecting cellular respiration rates](/ap-bio/frq-practice?id=6983d56febf1103b6c52808d&type=frq-6-analyze-data-short)
- [Enzyme function and heat stress on photosynthesis](/ap-bio/frq-practice?id=6983d5fdebf1103b6c528093&type=frq-6-analyze-data-short)
- [Compound Z inhibition of cellular respiration and ATP production](/ap-bio/frq-practice?id=6983d71debf1103b6c52809f&type=frq-6-analyze-data-short)
- [D1 protein damage and FtsH protease repair in photosynthesis](/ap-bio/frq-practice?id=6983d7aeebf1103b6c5280a5&type=frq-6-analyze-data-short)
- [HLS1 protein function in photosynthetic heat stress response](/ap-bio/frq-practice?id=6983d982ebf1103b6c5280bb&type=frq-6-analyze-data-short)
- [Light-dependent reactions and photosystem electron transport coupling](/ap-bio/frq-practice?id=6983da08ebf1103b6c5280c1&type=frq-6-analyze-data-short)

### Unit 4: Cell Communication and Cell Cycle (16)
- [Palbociclib effects on HER2+ cell cycle regulation](/ap-bio/frq-practice?id=69751e8f39cb567763bc69cf&type=frq-6-analyze-data-short)
- [Cell cycle checkpoint regulation under DNA replication stress](/ap-bio/frq-practice?id=6983cf7bebf1103b6c52804e&type=frq-6-analyze-data-short)
- [HGF signaling, MET receptor degradation, cell division regulation](/ap-bio/frq-practice?id=6983d033ebf1103b6c528057&type=frq-6-analyze-data-short)
- [Signal transduction, negative feedback, cell division](/ap-bio/frq-practice?id=6983d0cdebf1103b6c52805c&type=frq-6-analyze-data-short)
- [Quorum sensing signal transduction pathway mutations](/ap-bio/frq-practice?id=6983d2b8ebf1103b6c528070&type=frq-6-analyze-data-short)
- [DNA damage checkpoint regulation and protein dosage](/ap-bio/frq-practice?id=6983d401ebf1103b6c52807e&type=frq-6-analyze-data-short)
- [EGFR pathway mutations and drug inhibitor response](/ap-bio/frq-practice?id=6983d495ebf1103b6c528084&type=frq-6-analyze-data-short)
- [CDK1 regulation and cell cycle timing in yeast](/ap-bio/frq-practice?id=6983d52febf1103b6c52808a&type=frq-6-analyze-data-short)
- [EGFR signaling pathway and cell cycle regulation](/ap-bio/frq-practice?id=6983d5daebf1103b6c528092&type=frq-6-analyze-data-short)
- [EGFR inhibition and cell division regulation](/ap-bio/frq-practice?id=6983d678ebf1103b6c528097&type=frq-6-analyze-data-short)
- [DNA damage checkpoint regulation and protein dosage](/ap-bio/frq-practice?id=6983d71debf1103b6c5280a0&type=frq-6-analyze-data-short)
- [Signal transduction pathway mutations and cell division](/ap-bio/frq-practice?id=6983d7bcebf1103b6c5280a8&type=frq-6-analyze-data-short)
- [B-Raf mutation, drug resistance, melanoma cell proliferation](/ap-bio/frq-practice?id=6983d84febf1103b6c5280ae&type=frq-6-analyze-data-short)
- [Cell cycle regulation and CDK phosphorylation inhibition](/ap-bio/frq-practice?id=6983d8c7ebf1103b6c5280b2&type=frq-6-analyze-data-short)
- [DNA damage response and cell cycle checkpoints](/ap-bio/frq-practice?id=6983d955ebf1103b6c5280b9&type=frq-6-analyze-data-short)
- [p53-mediated cell cycle arrest following DNA damage](/ap-bio/frq-practice?id=6983d9f9ebf1103b6c5280c0&type=frq-6-analyze-data-short)

### Unit 5: Heredity (13)
- [Age-related cohesin decline and chromosomal segregation errors](/ap-bio/frq-practice?id=6974394706f04748fcb9c7ab&type=frq-6-analyze-data-short)
- [ASY1 protein function during meiotic heat stress](/ap-bio/frq-practice?id=6983d819ebf1103b6c5280ab&type=frq-6-analyze-data-short)
- [Synaptonemal complex mutations affecting crossing over and gamete viability](/ap-bio/frq-practice?id=6983d89debf1103b6c5280b1&type=frq-6-analyze-data-short)
- [Genetic control of meiotic crossing over frequency](/ap-bio/frq-practice?id=6983d938ebf1103b6c5280b7&type=frq-6-analyze-data-short)
- [Sister chromatid cohesion and meiotic chromosome segregation](/ap-bio/frq-practice?id=6983da5eebf1103b6c5280c7&type=frq-6-analyze-data-short)
- [Synaptonemal complex protein function in meiotic crossover formation](/ap-bio/frq-practice?id=6983daeaebf1103b6c5280cf&type=frq-6-analyze-data-short)
- [REC8 protein dosage and chromosome segregation accuracy](/ap-bio/frq-practice?id=6983dbd8ebf1103b6c5280db&type=frq-6-analyze-data-short)
- [SGO1 protein function in meiotic chromosome segregation](/ap-bio/frq-practice?id=6983dc89ebf1103b6c5280e6&type=frq-6-analyze-data-short)
- [Homologous chromosome recombination and MEI-2 protein levels](/ap-bio/frq-practice?id=6983dd0debf1103b6c5280f0&type=frq-6-analyze-data-short)
- [SPO11 protein levels and meiotic crossover frequency](/ap-bio/frq-practice?id=6983de42ebf1103b6c528103&type=frq-6-analyze-data-short)
- [Crossing over, chiasmata formation, meiotic errors](/ap-bio/frq-practice?id=6983decbebf1103b6c52810b&type=frq-6-analyze-data-short)
- [Meiotic recombination protein temperature sensitivity effects](/ap-bio/frq-practice?id=6983df6debf1103b6c528117&type=frq-6-analyze-data-short)
- [HSP90 protein function in meiotic chromosome segregation](/ap-bio/frq-practice?id=6983e087ebf1103b6c528129&type=frq-6-analyze-data-short)

### Unit 6: Gene Expression and Regulation (22)
- [Anthocyanin production and MYB10 gene dosage](/ap-bio/frq-practice?id=69751e8339cb567763bc69ce&type=frq-6-analyze-data-short)
- [PHO84 transporter structure and phosphate uptake function](/ap-bio/frq-practice?id=6983cf3bebf1103b6c52804b&type=frq-6-analyze-data-short)
- [Rubisco activase thermostability and photosynthetic performance](/ap-bio/frq-practice?id=6983cf73ebf1103b6c52804d&type=frq-6-analyze-data-short)
- [Crossing over frequency and SYN1 protein levels](/ap-bio/frq-practice?id=6983d5bcebf1103b6c528091&type=frq-6-analyze-data-short)
- [SGO1 protein function in meiotic chromosome separation](/ap-bio/frq-practice?id=6983d647ebf1103b6c528095&type=frq-6-analyze-data-short)
- [Gene mutation effects on microtubule stability](/ap-bio/frq-practice?id=6983d743ebf1103b6c5280a1&type=frq-6-analyze-data-short)
- [Galactose metabolism regulation and genetic mutations in yeast](/ap-bio/frq-practice?id=6983d874ebf1103b6c5280af&type=frq-6-analyze-data-short)
- [Gene regulation through promoter and translation initiation mutations](/ap-bio/frq-practice?id=6983d90bebf1103b6c5280b6&type=frq-6-analyze-data-short)
- [APX gene mutations and DNA damage response](/ap-bio/frq-practice?id=6983d99debf1103b6c5280bd&type=frq-6-analyze-data-short)
- [SGO1 protein levels and sister chromatid separation](/ap-bio/frq-practice?id=6983d9c2ebf1103b6c5280bf&type=frq-6-analyze-data-short)
- [Gene dosage effects on herbivore resistance mechanisms](/ap-bio/frq-practice?id=6983db0debf1103b6c5280d0&type=frq-6-analyze-data-short)
- [LIP1 gene mutations, enzyme production, catalytic activity](/ap-bio/frq-practice?id=6983db92ebf1103b6c5280d6&type=frq-6-analyze-data-short)
- [Catalase gene dosage and oxidative stress resistance](/ap-bio/frq-practice?id=6983dc2debf1103b6c5280e2&type=frq-6-analyze-data-short)
- [HRC1 protein levels and meiotic crossover formation](/ap-bio/frq-practice?id=6983dd96ebf1103b6c5280f9&type=frq-6-analyze-data-short)
- [GTR1 gene mutations and DNA damage response regulation](/ap-bio/frq-practice?id=6983de85ebf1103b6c528108&type=frq-6-analyze-data-short)
- [Gene regulation and proline synthesis enzyme expression](/ap-bio/frq-practice?id=6983df15ebf1103b6c528110&type=frq-6-analyze-data-short)
- [Gene regulation and transcription factor control mechanisms](/ap-bio/frq-practice?id=6983dfbeebf1103b6c52811a&type=frq-6-analyze-data-short)
- [Crossing over, genetic recombination, REC10 protein function](/ap-bio/frq-practice?id=6983e000ebf1103b6c528121&type=frq-6-analyze-data-short)
- [G6PD mutations affecting enzyme activity and protein levels](/ap-bio/frq-practice?id=6983e055ebf1103b6c528124&type=frq-6-analyze-data-short)
- [Heat stress survival and REG1 protein dosage](/ap-bio/frq-practice?id=6983e0daebf1103b6c52812e&type=frq-6-analyze-data-short)
- [Oxidative stress response and ATX1 protein dosage](/ap-bio/frq-practice?id=6983e16aebf1103b6c528137&type=frq-6-analyze-data-short)
- [Heat shock response and HSF1 protein levels](/ap-bio/frq-practice?id=6983e1f1ebf1103b6c528140&type=frq-6-analyze-data-short)

### Unit 7: Natural Selection (15)
- [Antibiotic resistance and metabolic fitness trade-offs](/ap-bio/frq-practice?id=69751e7c39cb567763bc69cd&type=frq-6-analyze-data-short)
- [Stickleback armor plate evolution in calcium-limited freshwater](/ap-bio/frq-practice?id=6983da16ebf1103b6c5280c2&type=frq-6-analyze-data-short)
- [Heavy metal tolerance and HMA4 protein dosage](/ap-bio/frq-practice?id=6983dab4ebf1103b6c5280cc&type=frq-6-analyze-data-short)
- [Adaptive evolution in cliff swallows under traffic selection](/ap-bio/frq-practice?id=6983db9debf1103b6c5280d8&type=frq-6-analyze-data-short)
- [Insecticide resistance evolution and fitness trade-offs](/ap-bio/frq-practice?id=6983dc1cebf1103b6c5280df&type=frq-6-analyze-data-short)
- [Peppered moth camouflage and industrial pollution adaptation](/ap-bio/frq-practice?id=6983dcb1ebf1103b6c5280e9&type=frq-6-analyze-data-short)
- [Plant adaptation to copper-contaminated soil environments](/ap-bio/frq-practice?id=6983dd2cebf1103b6c5280f2&type=frq-6-analyze-data-short)
- [Herbicide resistance mechanisms in weed populations](/ap-bio/frq-practice?id=6983ddbdebf1103b6c5280fa&type=frq-6-analyze-data-short)
- [Herbicide resistance mutations in Palmer amaranth weeds](/ap-bio/frq-practice?id=6983de56ebf1103b6c528104&type=frq-6-analyze-data-short)
- [Pesticide resistance evolution through genetic mutations](/ap-bio/frq-practice?id=6983def1ebf1103b6c52810d&type=frq-6-analyze-data-short)
- [Ace-1 gene mutation and organophosphate resistance trade-offs](/ap-bio/frq-practice?id=6983df6aebf1103b6c528116&type=frq-6-analyze-data-short)
- [Cadmium toxicity tolerance, MTP protein function](/ap-bio/frq-practice?id=6983e091ebf1103b6c52812b&type=frq-6-analyze-data-short)
- [Pyrethroid resistance mutations and fitness trade-offs](/ap-bio/frq-practice?id=6983e19febf1103b6c52813b&type=frq-6-analyze-data-short)
- [Zinc tolerance mutations in plant membrane transport genes](/ap-bio/frq-practice?id=6983e3dbebf1103b6c528160&type=frq-6-analyze-data-short)
- [Insecticide resistance mechanisms in mosquito populations](/ap-bio/frq-practice?id=6983e46aebf1103b6c528169&type=frq-6-analyze-data-short)

### Unit 8: Ecology (16)
- [Predator effects on herbivory and plant biomass](/ap-bio/frq-practice?id=69751eaf39cb567763bc69d1&type=frq-6-analyze-data-short)
- [Predator-prey dynamics in agricultural pest control](/ap-bio/frq-practice?id=6983daafebf1103b6c5280cb&type=frq-6-analyze-data-short)
- [Trophic cascades from wolf reintroduction](/ap-bio/frq-practice?id=6983dbd0ebf1103b6c5280da&type=frq-6-analyze-data-short)
- [Invasive garlic mustard disrupts mycorrhizal fungal relationships](/ap-bio/frq-practice?id=6983dc69ebf1103b6c5280e5&type=frq-6-analyze-data-short)
- [Invasive rats disrupting island ecosystem nutrient cycling](/ap-bio/frq-practice?id=6983dcecebf1103b6c5280ee&type=frq-6-analyze-data-short)
- [Nitrogen pollution effects on freshwater lake ecosystems](/ap-bio/frq-practice?id=6983ddeaebf1103b6c5280fe&type=frq-6-analyze-data-short)
- [Invasive garlic mustard disrupts mycorrhizal fungal associations](/ap-bio/frq-practice?id=6983de5debf1103b6c528106&type=frq-6-analyze-data-short)
- [Keystone predator role in intertidal community structure](/ap-bio/frq-practice?id=6983dee8ebf1103b6c52810c&type=frq-6-analyze-data-short)
- [Invasive plant disruption of mycorrhizal fungal associations](/ap-bio/frq-practice?id=6983df65ebf1103b6c528115&type=frq-6-analyze-data-short)
- [Invasive garlic mustard disrupts mycorrhizal fungal relationships](/ap-bio/frq-practice?id=6983dffcebf1103b6c52811f&type=frq-6-analyze-data-short)
- [Invasive lionfish, trophic cascades, coral reef destabilization](/ap-bio/frq-practice?id=6983e06bebf1103b6c528125&type=frq-6-analyze-data-short)
- [Coral bleaching, thermal stress, symbiotic algae loss](/ap-bio/frq-practice?id=6983e170ebf1103b6c528138&type=frq-6-analyze-data-short)
- [Invasive species impacts on native plant-fungal symbiosis](/ap-bio/frq-practice?id=6983e23debf1103b6c528144&type=frq-6-analyze-data-short)
- [Trophic cascades in freshwater ecosystems](/ap-bio/frq-practice?id=6983e3bcebf1103b6c52815e&type=frq-6-analyze-data-short)
- [Invasive plants disrupting mycorrhizal fungal associations](/ap-bio/frq-practice?id=6983e433ebf1103b6c528165&type=frq-6-analyze-data-short)
- [Invasive plant allelopathy disrupting mycorrhizal symbiosis](/ap-bio/frq-practice?id=6983e564ebf1103b6c528179&type=frq-6-analyze-data-short)

## Sample question

**Enzyme thermal stability and protein folding mutations**

Pectate lyase is an enzyme found in certain bacteria that degrades pectin in plant cell walls. The enzyme's function depends on its tertiary structure, which is maintained by interactions between amino acid R-groups.

Scientists identified a strain of bacteria with a mutation in the gene encoding pectate lyase. The mutation, labeled K128L, results in the substitution of lysine (which has a positively charged R-group) with leucine (which has a nonpolar R-group) at position 128 in the protein chain. To investigate the effect of this mutation, scientists purified both the wild-type (WT) and mutant (K128L) enzymes.

The scientists incubated both enzymes at a range of temperatures from 20°C to 60°C. They measured the relative enzymatic activity of each form (Figure 1A) and used spectroscopy to determine the percent of the protein that remained in its native, folded conformation at each temperature (Figure 1B).

Figure 1:
  Type: graph
  Caption: Figure 1. Temperature dependence of wild-type and mutant pectate lyase
  URL: https://kcbwzropdukwhmmvdylp.supabase.co/storage/v1/object/public/frq_stimulus/ap-bio/e20d7663-0791-480a-8608-32b42a2b64b8_fig1.jpg
  Placement: before-part
  Part Letter: A

Part A (1 point):
  Prompt: Based on Figure 1A, **identify** the temperature at which the wild-type (WT) enzyme functions at its maximum relative activity.
  Verb: identify

Part B (1 point):
  Prompt: Based on Figure 1B, **describe** the difference in the percent of folded protein between the wild-type (WT) and mutant (K128L) enzymes at 40°C.
  Verb: describe

Part C (1 point):
  Prompt: Scientists hypothesize that the K128L mutation reduces the thermal stability of the enzyme's tertiary structure. Use the data in Figures 1A and 1B to **support** the scientists' hypothesis.
  Verb: support

Part D (1 point):
  Prompt: Based on the chemical properties of the amino acid R-groups provided in the background, **explain** why the substitution of lysine with leucine results in the structural changes observed in Figure 1B.
  Verb: explain

Image URLs (1):
  - https://kcbwzropdukwhmmvdylp.supabase.co/storage/v1/object/public/frq_stimulus/ap-bio/e20d7663-0791-480a-8608-32b42a2b64b8_fig1.jpg

## Questions

**How many responses can I get scored?**

You can read every question without a plan. Your first scored response is included. A plan unlocks unlimited scoring.

**How do I describe data so it earns the point?**

Cite specific values and the direction of the change, like “increased from 2 to 5 mm per day.” Saying a value “went up” is usually too vague.

**Do I need to calculate anything?**

Sometimes, but rarely much. When you do, type your setup and the answer with its units.

**How is this different from the Scientific Investigation FRQ?**

This question centers on reading results and what they mean. The Scientific Investigation FRQ centers on how the experiment is designed.

## Related

- [Data Analysis FRQ exam guide](/ap-bio/ap-biology-exam/ap-bio-frq-short/study-guide/ap-bio-frq-short)
- [AP Biology Experimental Results FRQ practice](/ap-bio/frqs/experimental-results)
- [AP Biology Graphing FRQ practice](/ap-bio/frqs/graphing)
- [AP Biology Scientific Investigation FRQ practice](/ap-bio/frqs/scientific-investigation)
- [AP Biology Conceptual Analysis FRQ practice](/ap-bio/frqs/conceptual-analysis)
- [AP Biology Model Analysis FRQ practice](/ap-bio/frqs/model-analysis)
- [AP Biology FRQs](/ap-bio/frqs)
- Any question by id: the `get_frq` tool on the [Fiveable MCP server](/mcp/docs)

## About This Document

Canonical Fiveable pages are available as Markdown at the same path plus `.md`.

- [llms.txt](https://fiveable.me/llms.txt): index of Fiveable's sections and URL patterns
- [llms-full.txt](https://fiveable.me/llms-full.txt): complete subject and unit listing
- [MCP server](https://fiveable.me/mcp): call Fiveable as tools instead of fetching pages (`https://fiveable.me/api/mcp`)
- [MCP server for AP teachers](https://fiveable.me/mcp/teachers): a teacher's classes, assignments and AP-rubric grading (`https://fiveable.me/api/mcp/teacher`)