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🧬AP Biology
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🧬AP Biology

FRQ 5 – Analyze Model or Visual Representation (Short)
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Unit 1: Chemistry of Life
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This mapping reflects College Board's exam structure - each FRQ type tests specific skills that are taught in particular units.

Practice FRQ 1 of 201/20

5. Figure 1 shows a model of the interaction between the TATA-binding protein (TBP) and a segment of DNA during the initiation of transcription.

A.

Describe the feature of the DNA molecule that determines the specific genetic information it encodes.

Figure 1. TATA-binding protein (TBP) binds and bends a short DNA segment; Lysine and Arginine form ionic attractions to DNA phosphates and Phenylalanine intercalates between base pairs while bases are held together by hydrogen bonds.

Figure 1
B.

Based on Figure 1, explain how the chemical properties of the amino acids Lysine and Arginine facilitate the binding of TBP to the DNA molecule.

C.

Using the information in Figure 1, identify the type of chemical bond represented by the dotted lines between the nitrogenous bases: covalent bond, hydrogen bond, or ionic bond.

D.

Based on Figure 1, explain how a mutation in the TBP gene that replaces Lysine with Glutamic Acid (a negatively charged amino acid) would affect the ability of TBP to bind to DNA.

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Free Response Question Practice

This practice environment simulates the AP AP Biology Free Response Questions section. Here are some guidelines:

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