Fiveable
Fiveable

Topoisomerase

Definition

Topoisomerase is an enzyme that alters the supercoiled form of a DNA molecule. It helps in unwinding the DNA helix by cutting one or both strands, allowing it to unwind and then resealing it.

Related terms

DNA Gyrase: This is a type of topoisomerase that introduces negative supercoils (or relaxes positive supercoils) into DNA.

Helicase: An enzyme that separates DNA strands before replication can occur.

Ligase: An enzyme that connects two fragments of DNA to make a single fragment; it's like the glue for our genetic material.

"Topoisomerase" appears in:

Study guides (1)

  • AP Biology - 6.2 Replication

Practice Questions (1)

  • Which of the following is the role of topoisomerase during DNA replication?

collegeable - rocket pep

Are you a college student?

  • Study guides for the entire semester

  • 200k practice questions

  • Glossary of 50k key terms - memorize important vocab


Fiveable
About Us

About Fiveable

Blog

Careers

Code of Conduct

Terms of Use

Privacy Policy

CCPA Privacy Policy

Resources

Cram Mode

AP Score Calculators

Study Guides

Practice Quizzes

Glossary

Cram Events

Merch Shop

Crisis Text Line

Help Center

Stay Connected


© 2024 Fiveable Inc. All rights reserved.
AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.

About Us

About Fiveable

Blog

Careers

Code of Conduct

Terms of Use

Privacy Policy

CCPA Privacy Policy

Resources

Cram Mode

AP Score Calculators

Study Guides

Practice Quizzes

Glossary

Cram Events

Merch Shop

Crisis Text Line

Help Center

© 2024 Fiveable Inc. All rights reserved.

AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.